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What Causes Non-eosinophilic Asthma

What Causes Non-eosinophilic Asthma

Eosinophilic asthma is a type of asthma where the main problem is that the eosinophil cells, which are a type of white blood cell that is typically involved in the immune system's response to certain types of infections or allergies, begin to accumulate in the airways of the lungs. This can cause inflammation, which can make it harder to breathe and can lead to symptoms such as coughing, wheezing, shortness of breath, and chest tightness.

Eosinophilic Asthma Symptoms

3D Model of the Lungs and Airways

The symptoms of eosinophilic asthma can vary from person to person, but some common symptoms include:

  • Coughing, especially at night or early morning
  • Wheezing, which is a high-pitched sound when you breathe out
  • Shortness of breath, which can make it difficult to take a deep breath
  • Chest tightness or pain, which can feel like a heavy weight on your chest
  • Fatigue or weakness, which can be caused by having to work harder to breathe

If you are experiencing any of these symptoms, it is important to talk to your doctor. They can help you figure out if you have eosinophilic asthma and recommend appropriate treatment options.

Eosinophilic Asthma Diagnosis

Diagnosis and Management of Eosinophilic Asthma

Diagnosing eosinophilic asthma can be difficult because it can look and feel like other types of asthma. Your doctor may need to do some tests to confirm that you have eosinophilic asthma, such as:

  • Spirometry, which measures how much air you can inhale and exhale and how quickly you can do it
  • Peak flow testing, which measures how fast you can exhale air
  • FeNO testing, which measures the level of nitric oxide in your breath, which can be a sign of inflammation
  • Blood tests, which can check for the presence of eosinophil cells
  • Vocal cord function tests, which can check for any issues with your vocal cords that may be causing your symptoms

Based on the results of these tests, your doctor can determine if you have eosinophilic asthma and what the best treatment options are for you.

Eosinophilic Asthma Treatment

Managing eosinophilic asthma can involve a range of different treatment options, including:

  • Inhaled corticosteroids, which can reduce inflammation in the airways
  • Long-acting bronchodilators, which can help keep the airways open
  • Oral corticosteroids, which are sometimes used as a short-term treatment for severe inflammation
  • Biologic therapies, which are medications that target specific cells or molecules involved in the immune system's response to eosinophilic asthma
  • Lifestyle changes, such as avoiding triggers that can exacerbate symptoms, getting regular exercise, and eating a healthy diet

Your doctor can help you decide which treatment options are best for you based on the severity of your symptoms, the results of any testing, and other factors.


If you are experiencing symptoms of eosinophilic asthma, it is important to talk to your doctor. With the right diagnosis and treatment, it is possible to manage this condition and live a healthy, active life.